The role of perioperative treatment

Perioperative Treatment

Abbreviation: MIBC=muscle-invasive bladder cancer.

References: 1. Kim I-H, Lee H-J. Int J Mol Sci. 2021;22:7201. 2. Referenced with permission from the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) Bladder Cancer.V.4.2024. ©National Comprehensive Cancer Network, Inc. 2024. All rights reserved. Accessed July 10, 2024. To view the most recent and complete version of the guideline, go online to NCCN.org; 3. European Association of Urology. EAU guidelines on Muscle-invasive and Metastatic Bladder Cancer. 2024. Limited Update April 2024. https://d56bochluxqnz.cloudfront.net/documents/full-guideline/EAU-Guidelines-on-Muscle-Invasive-and-Metastatic-Bladder-Cancer-2024.pdf. Accessed July 2024; 4. Powles T, et al. Ann Oncol. 2022;33:244–258.

Perioperative treatment may be used to improve prognosis for patients with MIBC

Perioperative treatment includes neoadjuvant and adjuvant systemic treatments in addition to radical cystectomy.1 Perioperative treatment is recommended for patients who are eligible for chemotherapy and are fit for surgery to improve prognosis in patients with MIBC.2–4

Immunotherapy may be considered for eligible patients, regardless of whether they received previous platinum-based neoadjuvant treatment.2,3

Several immune checkpoint inhibitors are approved for the treatment of bladder cancer.

Abbreviation: MIBC=muscle-invasive bladder cancer.

References: 1. Kim I-H, Lee H-J. Int J Mol Sci. 2021;22:7201. 2. Referenced with permission from the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) Bladder Cancer.V.4.2024. ©National Comprehensive Cancer Network, Inc. 2024. All rights reserved. Accessed July 10, 2024. To view the most recent and complete version of the guideline, go online to NCCN.org; 3. European Association of Urology. EAU guidelines on Muscle-invasive and Metastatic Bladder Cancer. 2024. Limited Update April 2024. https://d56bochluxqnz.cloudfront.net/documents/full-guideline/EAU-Guidelines-on-Muscle-Invasive-and-Metastatic-Bladder-Cancer-2024.pdf. Accessed July 2024; 4. Powles T, et al. Ann Oncol. 2022;33:244–258.