Signs and symptoms of MIBC

Most Common Symptoms of MIBC

Abbreviation: MIBC=muscle-invasive bladder cancer.

References: 1. Referenced with permission from the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) Bladder Cancer.V.4.2024. ©National Comprehensive Cancer Network, Inc. 2024. All rights reserved. Accessed July 10, 2024. To view the most recent and complete version of the guideline, go online to NCCN.org. 2. European Association of Urology. EAU guidelines on Muscle-invasive and Metastatic Bladder Cancer. 2024. Limited Update April 2024. https://d56bochluxqnz.cloudfront.net/documents/full-guideline/EAU-Guidelines-on-Muscle-Invasive-and-Metastatic-Bladder-Cancer-2024.pdf. Accessed July 2024. 3. Powles T, et al. Ann Oncol. 2022;33:244–258. 4. Bladder Cancer Signs and Symptoms. https://www.cancer.org/cancer/types/bladder-cancer/detection-diagnosis-staging/signs-and-symptoms.html. Accessed July 2024.

MIBC is predominantly associated with the presence of blood in the urine and changes in urinary habits

The most common symptom of MIBC is haematuria. This can be detected as a visible change in the colour of urine or through urinalysis. Additionally, blood may or may not be continually present.1–4

Changes in urinary habits can also indicate MIBC and can include a change in urinary frequency or urgency. Irritation or pain while urinating can also be a symptom of MIBC.1–4

Many of the symptoms associated with MIBC can overlap with other, benign conditions but all patients with persistent symptoms should be evaluated for MIBC.1–4

Abbreviation: MIBC=muscle-invasive bladder cancer.

References: 1. Referenced with permission from the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) Bladder Cancer.V.4.2024. ©National Comprehensive Cancer Network, Inc. 2024. All rights reserved. Accessed July 10, 2024. To view the most recent and complete version of the guideline, go online to NCCN.org. 2. European Association of Urology. EAU guidelines on Muscle-invasive and Metastatic Bladder Cancer. 2024. Limited Update April 2024. https://d56bochluxqnz.cloudfront.net/documents/full-guideline/EAU-Guidelines-on-Muscle-Invasive-and-Metastatic-Bladder-Cancer-2024.pdf. Accessed July 2024. 3. Powles T, et al. Ann Oncol. 2022;33:244–258. 4. Bladder Cancer Signs and Symptoms. https://www.cancer.org/cancer/types/bladder-cancer/detection-diagnosis-staging/signs-and-symptoms.html. Accessed July 2024.