MIBC overview
Muscle-invasive bladder cancer (MIBC) is a locally advanced stage of bladder cancer
Bladder cancer is the ninth most common cancer with around 2 million people living with the disease worldwide.2 Bladder cancer predominantly affects people over 55 years of age and is more common in men.3
NMIBC is the earliest stage of bladder cancer where the tumour is confined to the inner lining of the bladder and accounts for around 75% of cases.4,5
MIBC comprises ~25% of newly diagnosed bladder cancers.5 MIBC is a locally-advanced stage of bladder cancer that has penetrated the bladder muscle wall and can involve tumour invasion into the perivesical tissue and nearby lymph nodes.3,4
Metastatic bladder cancer is the most advanced stage of bladder cancer where the tumour has spread to adjacent organs and tissues, accounting for around 5% of cases.3,6
Despite the curative intent of radical cystectomy, up to 50% of patients may still experience recurrence or disease progression within 5 years.7,8 Therefore, the aim of MIBC treatment is to halt disease recurrence and progression.
